Elaborate Course: Clinical Epidemiology
Course Director:LinaWang, MD, PhD, Associate Professor
School of Public Health, Southeast University
Department of Epidemiology and Biostatistics
PHS Building, Room 411, 210009
Telephone: (025) 83272569
Co-lecturers: Prof. Juan Zhang and Xiaojin Yu
I. Course Introduction:
Clinical Epidemiology is directed to MBBS students interested on the investigation of the occurrence and consequences of disease in clinical practice. This course expands on the knowledge and abilities developed in introduction to Clinical Epidemiology. The goal of this course is to provide clinical students with an opportunity to learn about the rationale and use of study designs that built in clinical epidemiologic research (experimental studies, case-control studies, and cohort studies). The main emphasis of this course is on the design and interpretation of clinical epidemiologic studies. The course will include hands-on experience in the evaluation of epidemiologic evidence, the analysis of epidemiologic data, and the discussion of strategies aimed to improve study validity and efficiency. Most lectures will be followed by a seminar session.
II. Teaching Syllabus (including the contents of chapters and sections)
I. Introduction (3h)
II. Epidemiology measure (3h);
III. Descriptive study (3h)
IV. Case-control study (3h)
V. Cohort study (3h)
VI. Clinical trial and disease prognosis (3h)
VII. Screening and diagnostic tests (3h)
VIII. Causal inference (3h)
IX. Design of epidemiology studies (3h)
X. Evidence-based medicine (3h)
XI Mata-analysis (3h)
XII Seminar (3h)
Lab 1: Epidemiology measure & Descriptive study (4h)
Lab 2: Case-control study &Cohort study (4h)
Lab 3: Design and analysis of clinical trial research and disease prognosis (4h)
Lab 4: Meta- analysis and research design(4h)
III. Teaching Schedule
Clinical trial and disease prognosis
Screening and diagnostic tests
Design of epidemiology studies
Epidemiology measure & Descriptive study
Case-control study &Cohort study
Design and analysis of clinical trial research and disease prognosis
Meta- analysis and research design
Assessment Methods:Student evaluation will be based on the final exam(70%), little quizes(30%), and discussions.
Policies:- Course readings should be completed prior to the start of the corresponding lecture.
- Homework must be handed in to the instructor on time.
- Students are encouraged to discuss course contents with each other.
- Students should expect to be individually asked to participate in the class discussions
- Hand outs and homework assignments will be delivered by e-mail: firstname.lastname@example.org.
Textbook & references:
1. Clinical Epidemiology, Self-designed Teaching Material, Southeast University.
2. Robert H Fletcher,Suzanne W Fletcher, Grant S Fletcher. Clinical Epidemiology, 5th edition,Wolters Kluwer.2014.
1.Introduction.pdf2.Measurement of the disease.pdf3. descriptive study.pdf4.case-control study.pdf5.Cohort Study.pdf6. Clinical trial.pdf7.screening and diagnostic test.pdf8. epidemiology methods and causal inference.pdf9.potential error(final).pdf10. introduction-to-ebm(yuxj).pdf11.Systematic Reviews meta-Analysis(final).pdf