Elaborate Course:Molecular Biology
I.Course Introduction (including teaching goals and requirements) within 300 words:
The students can grasp the basic knowledge of molecular biology, and are familiar with the principle of molecular biology technology; know development of it and application in medical.
II.Teaching Syllabus (including the content of chapters and sections. A sheet can be attached):
I Introduction 3h
1 A Brief History
2 The Molecular Nature of Genes
3 An Introduction to Gene Function
II Methods in Molecular Biology 3h
4 Molecular Cloning Methods
5 Molecular Tools for Studying Genes and Gene Activity
III Transcription in Prokaryotes 4h
6 The Transcription Apparatus of Prokaryotes
7 Operons: Fine Control of Prokaryotic Transcription
8 Major Shifts in Prokaryotic Transcription
9 DNA-Protein Interactions in Prokaryotes
IV Transcription in Eukaryotes 5h
10 Eukaryotic RNA Polymerases and their Promoters
11 General Transcription Factors in Eukaryotes
12 Transcription Activators in Eukaryotes
13 Chromatin Structure and Its Effects on Transcription
V Posttranscriptional Events 3h
14 Posttranscriptional Events I: Splicing
15 Posttranscriptional Events II: Capping and Polyadenylation
16 Posttranscriptional Events III: Other Events
VI Translation 3h
17 The Mechanism of Translation I: Initiation
18 The Mechanism of Translation II: Elongation and Termination
19 Ribosomes and Transfer RNA
VII DNA Replication, Recombination, and Transposition 6h
20 DNA Replication I: Basic Mechanism and Enzymology
21 DNA Replication II: Detailed Mechanism
22 Homologous Recombination
23 Site-Specific Recombination and Transposition
VIII OMICs 3h
IX RNA regulation 3h
28 small nuclear RNA (snRNP's)
29 SRP (signal recognition particle)
30 small nucleolar RNA (snoRNA)
31 Micro RNAs [miRNA]
X Molecular Biology of Virus 3h
33 Gene, molecular mechanism of virus infection
34 Diagnosis and treatment, vaccine and vector
XI Discussions 2h
XII Examination 2h
Introduction (A Brief History, The Molecular Nature of Genes, An Introduction to Gene Function, HGP)
Methods in Molecular Biology (Molecular Cloning Methods, Molecular Tools for Studying Genes and Gene Activity)
Transcription in Prokaryotes (The Transcription Apparatus of Prokaryotes, Operons: Fine Control of Prokaryotic Transcription, Major Shifts in Prokaryotic Transcription, DNA-Protein Interactions in Prokaryotes)
Transcription in Eukaryotes (Eukaryotic RNA Polymerases and their Promoters, General Transcription Factors in Eukaryotes, Transcription Activators in Eukaryotes, Chromatin Structure and Its Effects on Transcription)
Posttranscriptional Events (Posttranscriptional Events I: Splicing, Posttranscriptional Events II: Capping and Polyadenylation, Posttranscriptional Events III: Other Events)
Translation (The Mechanism of Translation I: Initiation, The Mechanism of Translation II: Elongation and Termination, Ribosomes and Transfer RNA)
DNA Replication, Recombination, and Transposition (DNA Replication I: Basic Mechanism and Enzymology, DNA Replication II: Detailed Mechanism, Homologous Recombination, Site-Specific Recombination and Transposition)
OMICs (Genomics, Proteomics, Transcriptomics, Metabolomics, Informatics)
RNA regulation (small nuclear RNA, SRP, small nucleolar RNA, Micro RNAs)
Molecular biology of virus (Classification, Gene, molecular mechanism of virus infection, diagnosis and treatment, vaccine and vector)
Note: 1.Above one, two, and three items are used as teaching Syllabus in Chinese and announced on the Chinese website of Graduate School. The four and five items are preserved in Graduate School.
2. Course terms: Spring, Autumn, and Spring-Autumn term.
3. The teaching languages for courses: Chinese, English or Chinese-English.
4. Applicable range of discipline: public, first-class discipline, second-class discipline, and third-class discipline.
5. Practice includes: experiment, investigation, research report, etc.
6. Teaching methods: lecture, seminar, practice, etc.
7. Examination for degree courses must be in paper.
8. Teaching material websites are those which have already been announced.
9. Brief introduction of chief lecturer should include: personal information (date of birth, gender, degree achieved, professional title), research direction, teaching and research achievements. (within 100-500 words)